Microdosis can be very beneficial and is usually achieved by ingesting 0.05-0.25 grams of the psilocybin mushroom. It is better to experiment as everyone has a different level of tolerance power.
The tolerance can depend on many factors including your body weight, your neurophysiology, the strength of the mushrooms you eat and you can read more here to know about other factors.
Microdoses help to activate your mind at the fastest level by taking 0.1 grams of dose. Ideally, you should calibrate the dose so that it arrives at the right place. However, the more conservative your approach, it may take a few tries to get started.
As a rule of thumb, you need to measure the dosage based on your body weight. So if you weigh less than 100 pounds you should start with 0.1-0.15 grams and see if this works for you. For people weighing more than 200 pounds, 0.3 grams should be sufficient, and so on.
Of course, you can't weigh it without a precision scale, but these little tricks will help you get to grips with a kitchen scale. Suppose you have a few grams of mushrooms and you want 10 microdoses of 0.1 g each.
All you have to do is weigh 1 gram on a kitchen scale and then use a knife to divide the pile into 10 optically identical mini stacks. It won't be exactly 0.1 g, but it will be very close.
Lastly, remember that it's better to play it safe. If you are trying any type of dosage, it is best to start small and increase it so you know exactly when you hit the sweet spot.